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ANTI - ENDOMISIO - Anticorpos (IgA) - Exames - Rocha Laboratório Total - Patologia, Análises Clínicas, Biologia Molecular e Centro de Referência em Imunizações

Laboratório Rocha

Rocha Online

Código: ENDOA

Nome: ANTI - ENDOMISIO - Anticorpos (IgA)

Material: soro

Volume: 2.0 mL

Método: Imunofluorescencia indireta

Volume Laboratorial: 2.0 mL

Rotina: 3ª e 5ª feira

Resultado em: 24h

Temp.: Sob refrigeração

Interpretação: Uso: diagnóstico de doença celíaca. Doença celíaca e dermatites herpetiformes são doenças caracterizadas como enteropatias glúten-sensíveis. Aproximadamente 70% dos pacientes com dermatites herpetiformes e mais do que 95% dos pacientes com doença celíaca ativa demonstram a presença de anticorpos IgA+IgG. Nestes pacientes, após dieta livre de glúten, os anticorpos decrescem ou desaparecem. A pesquisa de anticorpos anti endomísio IgA+IgG e anticorpos anti gliadina detecta 100% dos casos de doença celíaca. SENSIBILIDADE E ESPECIFICIDADE DO ANTICORPO ANTI-ENDOMÍSIO NA DOENÇA CELÍACA - REPORTADO NA LITERATUR Autor, revista, ano SENSIBILIDADE ESPECIFICIDADE Ferreira M, et al. Gut 1992 100% 100% Corrao G et al. Gut 1994 97,7% 100% Carroccio A, et al. Scand J Gastroenterol 1996 97,0% 100% Valdimarsson T, et al. Dig Dis Sci 1996 74,0% 100% Bottaro G, et al. J Ped Gastr Nutr 1997 96,0% 100% SENSIBILIDADE E ESPECIFICIDADE DO ANTICORPO ANTI-GLIADINA NA DOENÇA CELÍACA - REPORTADO NA LITERATURA Autor, Revista, Ano SENSIBILIDADE ESPECIFICIDADE Burgin-Wolf A, et al. Eur J Pediatr 1989 96% (IgA/G) 97% (IgA/G) Corrao G, et al. Gut 1994 91% (IgA) 89% (IgA) Picarelli A, et al. It J Gastroenterol 1996 58% (IgA) 86% (IgA) 61% (IgG) 86% (IgG) 68% (IgA/G) 86% (IgA/G) Sulkanen S, et al. Gastroenterology 1998 85% (IgA) 82% (IgA) 69% (IgG) 73% (IgG)

Referência: Não reagente

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